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Pakistan Journal of Pharmaceutical Sciences. 2018; 31 (6 Special): 2885-2889
in English | IMEMR | ID: emr-205129

ABSTRACT

To explore the application of controlled hypotension in cesarean section of pregnant women with high-risk hemorrhage. 75 cases were randomly divided into three groups: controlled hypotension Group 1 [Group H1], controlled hypotension Group 2 [Group H2] and normal blood pressure Group [Group N]. The preoperative general data, intraoperative conditions, postpartum concurrent Symptoms and other indicators of all the cases in three groups were compared. The Apgar score, umbilical arterial blood gas and other indicators of the newborns were detected. There was no significant difference in the preoperative general data, Apgar score at 1 min and 5 min, the level of PH, PaO2, PaCO2 among the three groups [P>0.05]. The intraoperative blood transfusion volume in group H1 and group H2 decreased significantly than that in-group N [P<0.05], but there was no significant difference between group H1 and group H2 [P>0.05]. Compared with group H1, the red cell transfusion volume in-group H2 was significantly reduced [P<0.05]. There was no significant difference in other intra-operative indexes such as bleeding volume, infusion volume, patient urine volume and hospitalization days among the three groups [P>0.05]. Controlled hypotension [within 5 min of MAP down to 70% of basal blood pressure] can reduce the incidence of hemorrhage and postpartum hemorrhage during cesarean section in high-risk bleeding pregnant women and which had no bad effects on the incidence of complications and umbilical arterial blood gas indicators compared with control group

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